THORNE PharmaGABA-250 - GABA Supplement - 250 mg Natural Source Gamma-Aminobutyric Acid - Promotes a Calm, Relaxed, Focused State of Mind* - 60 Capsules

I did a sleep/stress test and learned that my cortisol was upside down.Low in the morning - so sluggish and can't get out of bed, even at 10 AM, I could only get up because I HAD TO.High in the evening - laying in bed, almost like I have a panic attack - so alert, I can't sleep.I'm taking a few supplements now and altering my diet and lifestyle to reduce my cortisol levels. I want them high in the morning, so I can spring out of bed and low in the evening to lay down and rest.This PharmaGABA-250 is one of the supplements I started taking with the guidance of a functional nutritionist after we saw my cortisol labs.I can report that I noticed the effect of this supplement. I took it with a small glass of water about 30 minutes before bedtime. Fifteen minutes in, I started to feel very heavy - like how I feel when I'm sleepy. I did my bedtime routine - put on PJs, washed my face, brushed my teeth, etc., and got into bed.I woke up the next day a few minutes BEFORE my alarm. I felt refreshed, perfect.I've been taking this every night and have had great success, except one night when I had some sugar close to bedtime (I had cocoa), that disrupted the experience. So, GABA helps a lot, but diet also impacts me.One dose-related caution I would use is that my partner wanted to try this supplement to help him sleep when stressed about work. He couldn't stop thinking about work. He took one pill (same as I do), and he slept. He felt very heavy the next day and struggled with work in the morning, which was the exact opposite effect he wanted. He might benefit from Thorne's lower (100mg) dose. We've ordered it, but he hasn't tried it yet. If you're not sure how much you need, I recommend starting with the lower dose because you can always take more of them if you find you need them.

This is my first time purchasing this dosage; pricey but cheaper than taking 2 at the lower dose. First of all, I use muscle testing to figure out what I need, how much and what brand would be best for me. Out of lots of options on Amazon, this brand has consistently tested as the best option and I have used them for various things for a couple of years. So I definitely trust their quality. I can’t compare them in any other way or give evidence, only consistent experience and what I have seen with muscle testing. The interesting part of that is that I have gone into health food stores before and muscle tested options and nothing has tested strong. And I had to look at Amazon to find something. That says a lot to me. Plus Amazon usually tends to have better prices generally than health food stores. With Prime and considering gas and time, Amazon is usually the better option if it isn’t an emergency.I have been using this for stress and anxiety issues and take it in the morning. I know others who take it at night to help with sleep. It has definitely helped. My daughter has also been taking it and feels like it really makes a difference for her as well. I also have recommended this to friends. Wish I had known about it sooner!

My physician recommended this for my anxiety. I had tried many other supplements on my own that all promised to calm, relax, help focus, help sleep, etc. I have struggled with insomnia, anxiety and panic attacks for the past 4 years. I am currently taking Xanax to help manage my symptoms but I do not want to stay on Xanax the rest of my life. This is the only product that I have found that actually works. It keeps the anxiety from getting out of control. I can usually just breathe through it now. And this supplement has allowed me to start dosing back on Xanax. I take PharmaGaba 3 times daily as recommended. It does not make me sleepy but rather just levels everything out. It does not feel like I took a Xanax which you definitely feel the affects of but rather I noticed that I just felt calm throughout the day. No ups and downs, no jitters, no racing heart, no fight or flight feeling. It really has given me hope that I will be able to get off of Xanax and start to manage my anxiety in a healthier way.

This helps with brain firing it relaxes you but not in the sleepy sense. I usually take one to two before I go to bed or two in the morning before I start my day. It makes me feel less stressed.

My research shows me that this is a high quality product. And I don't base that on widely varying reviews.If GABA is actually what you need, then this supplement should help. If it is not what your particular situation requires, it will probably do nothing and you could then end your GABA supplementation experiment.My experience is that taking 250mg on an empty stomach in the morning gives me an uneasy feeling in about 10 minutes and subsides in about 20. I cut back to 100mg and don't get that feeling.I don't take it later in the day, as GABA can increase your mental focus and keep you awake.I was on Xanax VERY INFREQUENTLY in the past and GABA supplementation has replaced that medication for me.You may also consider a HIGH QUALITY vitamin B supplement in your supplementation experiments.I recommend this product based only on my personal experience. Your physiology may give you a totally different experience.

I have used this brand for Gaba 250 along with other supplements. Works much better than other brands so is worth th cost.

No side effects. Really helps with calming and focus. Highly recommend.

12-3-24 update: Seller was good about contacting me and fully refunded my purchase...thank you...tried these a few nights in a row...did not work for me